Hydrea (Hydroxyurea) is indicated for sickle cell anemia, which reduces painful episodes associated with the disease. This medication reduces the need for blood transfusions as well. It is also used in the treatment of several types of cancers such as melanoma, chronic myelocytic leukemia, ovary cancer, and squamous cell carcinomas. The dosage of Hydrea prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.  Hydrea can be taken with or without food. Take each dose with a full glass of water. If your physician has instructed or directed you to take Hydrea medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.