What is Locoid used for?

Locoid Lipocream 0.1% is used as a topical treatment for several moderate to severe inflammatory skin conditions, both chronic and acute. These include various forms of dermatitis, such as eczema, also called atopic dermatitis as there is a predisposition due to an inherited atopic tendency; also lichen simplex a form of dermatitis made worse by constant itching and scratching. Psoriasis is thought to be an autoimmune skin condition characterised by a chronic scaly rash. Locoid Lipocream 0.1% helps relieve symptoms common to inflammatory skin conditions such as itching, redness, dryness, crusting, scaling and discomfort, and is particularly helpful for dry skin.

How does Locoid work?

Locoid Lipocream contains the synthetic corticosteroid Hydrocortisone 17-butyrate, which is a potent anti-inflammatory with anti-pruritic properties (anti-itching). Hydrocortisone 17-butyrate in Locoid Lipocream 0.1% works by blocking the action of phospholipase A2, the first enzyme involved in the synthesis of prostaglandins and leukotrienes, which are hormone-like substances involved in the inflammatory process; also cyclooxygenase (COX 1 and COX 2), the enzymes specifically involved in prostaglandin production. Blocking the production of inflammatory chemicals prevents the swelling and redness characteristic of inflammation and the itching and rash formation that can happen as a result of inflammation.

What does Locoid contain?

Locoid Lipocream 0.1% contains the active ingredient hydrocortisone 17-butyrate, a synthetic corticosteroid used as a topical treatment for inflammatory skin conditions. It also contains cetostearyl alcohol, macrogol (25) cetostearyl ether, light liquid paraffin, white soft paraffin, citric acid (anhydrous), purified water, sodium citrate (anhydrous), propyl parahydroxybenzoate, benzyl alcoho

Treating dermatitis and eczema with Locoid

Locoid Lipocream 0.1% contains hydrocortisone 17-butyrate, a synthetic corticosteroid that is used as a topical treatment for various forms of dermatitis, including atopic eczema, an inherited, chronic, inflammatory and itchy skin condition where the skin reacts abnormally to irritants and is common in children. Hydrocortisone 17-butyrate in Locoid Lipocream 0.1% works by blocking the enzymes involved in the production of hormone-like substances called leukotrienes and prostaglandins, which cause inflammation. This helps relieve symptoms such as itching, redness, dryness, crusting, scaling and discomfort.

Locoid for Psoriasis

Locoid Lipocream 0.1% contains Hydrocortisone 17-butyrate, a synthetic corticosteroid that is used as a topical treatment for the skin condition psoriasis, which thought to be an autoimmune skin disorder characterised by a chronic scaly rash due to inflammation and an increased turnover of skin cells. Hydrocortisone 17-butyrate in Locoid Lipocream 0.1% works by blocking the enzymes involved in the production of hormone-like substances called leukotrienes and prostaglandins, which cause inflammation. This helps relieve symptoms such as itching, redness, dryness, crusting, scaling and discomfort.

What are the side effects of Locoid?

The most commonly reported side effects when taking Locoid Lipocream include: burning, itching, irritation and dryness at the site of application, thinning or discolouration of the skin, rebound effect, which is a flare up of the original skin condition when you stop using locoid and can lead to a dependency on the medication, delay of the wound healing. Long-term use of Locoid Lipocream may cause the adrenal glands, which produce endogenous (naturally occurring) corticosteroids, to stop working efficiently and this may slow down the growth rate in children

When should Locoid not be used?

You should not use Locoid Lipocream 0.1% if you:

• are allergic to Hydrocortisone 17-butyrate or any ingredients in Locoid Lipocream
• are pregnant or are breastfeeding, without discussion with your doctor
• have a viral infection of the skin, tuberculosis, acne rosacea (a chronic skin condition), perioral dermatitis (facial rash around the mouth), fungal skin infections and ulcerative conditions
• have damaged skin

How should Locoid be used?

You should apply a small amount of your Locoid Lipocream 0.1% to the affected area of skin 1-4 times daily or as recommended by your doctor. Gently rub into the skin and cover with an occlusive dressing only if recommended by your doctor. Wash your hands after use and avoid contact with the eyes. Do not use Locoid Lipocream on the eye-lids as this can increase risk of glaucoma or cataracts. You should continue to use your Locoid Lipocream for as long as recommended by your doctor and depending on your condition; long term continuous use should be avoided as it can cause problems, particularly in children.

How long should you use Locoid?

You should continue to use your Locoid Lipocream for as long as recommended by your doctor and depending on your condition; long term continuous use should be avoided as it can cause problems, particularly in children.

Missed dose of Locoid

If you miss a dose of Locoid Lipocream apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose.

How should Locoid be stored?

You should store your Locoid below 25°C in a cool dry place.